liver cancer

Taiwan liver cancer a new study found. Yangming University Institute of microbiology and immunology, Professor Chen Min team, successfully developed glycine methyltransferase enzyme (GNMT) gene knockout mice and found that the use of ultrasound to track the growth of rats removed 14 months later, there will be Liver tumor, confirmed GNMT disappeared and liver cancer genes related to the occurrence.

According to Taiwan's "China Times" reported that the results of this study have been published in leading international medical journals liver cancer "of the liver". Chen Min pointed out that the formation of liver cancer complicated process, the research team of Charity Hospital and Taipei, 25 from liver cancer patient's pathology biopsy study found that 24 patients with liver samples, completely unable to find GNMT genes, gene apparent GNMT And closely related to liver cancer.

But in the end is to cause liver cancer disappeared GNMT » Or liver cancer after, GNMT before disappearing » Chen Min said that five years ago, the research team nurture GNMT gene knockout mice, the mice from the body GNMT gene completely removed, and then ultrasound observed liver cancer formation process.

The results showed that seven out of rats GNMT was born 19 months later, all have a spontaneous liver cancer, the incidence rate of 100 per cent; three of the mouse to the first 19 months after a liver cancer. This confirms the formation of liver cancer in GNMT play an important role in gene expression inhibited or destroyed if it disappeared, there is a high probability of liver cancer. And the incidence of liver cancer, and there have been noticeable gender differences.

Chen Min stressed that under normal circumstances, GNMT gene in women's performance is the number of men's eight times the rate of male liver cancer in women is 3-8 times. However, the research team GNMT gene knockout mice, rats and mice the same as the incidence of liver cancer, and even rats is higher than the rat, confirmed that women are less prone to liver cancer is likely to have GNMT of protection. GNMT gene expression women more than men, with male hormones inhibit GNMT relevant.